Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 26;119(40):e2204716119. doi: 10.1073/pnas.2204716119

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 the Author(s). Published by PNAS.

This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

PMC Copyright notice

Fig. 4. — The rapid evolution of pluripotency-associated SEs in mammals. (A) Numbers of human, pig, and mouse pluripotency-associated SEs and TEs. (B) SE- and TE-linked genes of humans (red), pigs (blue), and mice (green). (C) GO analysis of the shared enhancer-linked genes in three species. (D) Phylogenetic analysis of the SE sequences of humans, pigs, and mice. The H3K27ac, OCT4, and SOX2 ChIP-defined SEs in porcine PSCs were identified and subjected to conservation analysis in the genomes of humans and mice. The SE-linked genes are listed. (E and F) Characteristics of the SE linked to the gene TEX14 (SE-TEX14) in pigs. SE-TEX14 shows different proximal genes in humans and mice and displays high OCT4 occupation. h, human; m, mouse; p, pig.