Table 1.
Results of THP-1 cells engulfed RBCs.
| Phagocytosis rates of RBCs (100%) | p value | |||||
|---|---|---|---|---|---|---|
| Untreated RBCs | 42°C-incubated RBCs | IgG-opsonized RBCs | 1 | 2 | 3 | |
| Wild-type THP-1 | 13.12 ± 0.34 | 31.56 ± 0.41 | 44.54 ± 0.06 | ∗∗ | ∗∗ | ∗∗ |
| shNC THP-1 | 13.50 ± 0.12 | 31.72 ± 1.00 | 44.87 ± 0.40 | ∗∗ | ∗∗ | ∗∗ |
| ID3 THP-1 | 4.85 ± 0.19 | 18.15 ± 0.68 | 23.02 ± 0.23 | ∗∗ | ∗∗ | ∗∗ |
| p value | ||||||
| 4 | Ns | Ns | Ns | |||
| 5 | ∗∗ | ∗∗ | ∗∗ | |||
| 6 | ∗∗ | ∗∗ | ∗∗ | |||
p value, 1: untreated RBCs vs. 42°C-incubated RBCs; 2: untreated RBCs vs. IgG-opsonized RBCs; 3: 42°C-incubated RBCs vs. IgG-opsonized RBCs; 4: wild-type THP-1 vs. shNC THP-1; 5: Wild-type THP-1 vs. ID3 THP-1; and 6: shNC THP-1 vs. ID3 THP-1. ∗∗p < 0.01, ns: not significant.