Figure 4.

Cardiovascular outcomes during follow-up. (a) Incidence rates during follow-up (y-axis) of outcomes (x-axis) by the presence of CKD. ∗indicates P < 0.05; ∗∗ indicates P < 0.01; ∗∗∗indicates P < 0.001. (b) Adjusted hazard ratios (circles) with 95% confidence intervals (bars) for outcomes (y-axis) in the CKD group versus the no CKD group. Models include adjustment for age, sex, race, ethnicity, current tobacco use, prevalent diabetes and coronary artery disease, prior MI and CLI, mode of revascularization, and antiplatelet and statin therapy use. CI, confidence interval; MI, ; MACE, major adverse cardiovascular events; MACLE, major adverse cardiovascular and limb event.