Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 7;12:16899. doi: 10.1038/s41598-022-21345-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Knockdown of CAMSAP2 inhibited colorectal cancer cell migration and invasion. (A) The mRNA level of CAMSAP2 in SW-620 and SW-480 cells transduced with CAMSAP2 shRNAs (shCAMSAP2 #1 and shCAMSAP2 #2) or shNC was detected using qRT-PCR analysis. (B) Western blot analysis of the protein levels of CAMSAP2 in SW-620 and SW-480 cells transduced with CAMSAP2 shRNAs or shNC. (C) Silencing CAMSAP2 suppressed colorectal cancer cell migration measured using wound healing assay. Left: representative images of wound scratch. Right: histograms represent the analysis of the wound healing rate. Scale bar: 100 μm. (D) Knocking down CAMSAP2 hampered the migration of colorectal cancer cells detected by transwell migration assay. Scale bar: 100 μm. (E) Silencing CAMSAP2 suppressed the invasion of colorectal cancer cells examined using transwell invasion assay. Scale bar: 100 μm. (F) Silencing CAMSAP2 inhibited the lung metastasis of colorectal cancer in nude mice. Scale bar: 500 μm. ***P < 0.001.