Table 2.
Summary statistics for EQ-5D-3L by BMI category and changes in EQ-5D-3L between trial time-points stratified by % weight change
| Group categories | Mean EQ-5D-3L at baseline stratified by BMI category | |||
|---|---|---|---|---|
| N | Mean | Standard deviation | F-statistic (p value) | |
| All participants | 1209 | 0.788 | 0.252 | |
| 28–30 kg/m2 | 184 | 0.846 | 0.208 | 19.66 (p < 0.000) |
| 30–35 kg/m2 | 577 | 0.813 | 0.226 | |
| ≥ 35 kg/m2 | 448 | 0.731 | 0.288 | |
| Changes in EQ-5D-3L from baseline to 3 months | ||||
|---|---|---|---|---|
| % weight change from baseline to 3 months | N | Mean | Standard deviation | F-statistic (p value) |
| All participants | 883 | 0.0047 | 0.1700 | |
| > 10% weight gain | 1 | 0.0710 | 0.0000 | 1.06 (0.3796) |
| 5–10% weight gain | 1 | − 0.1920 | 0.0000 | |
| < 5% weight gain | 82 | − 0.0149 | 0.1787 | |
| < 5% weight loss | 408 | 0.0052 | 0.1702 | |
| 5–10% weight loss | 307 | 0.0015 | 0.1740 | |
| > 10% weight loss | 84 | 0.0346 | 0.1411 | |
| Changes in EQ-5D-3L from baseline to 12 months | ||||
|---|---|---|---|---|
| % weight change from baseline to 12 months | N | Mean | Standard deviation | F-statistic (p value) |
| All participants | 722 | − 0.0020 | 0.1945 | |
| > 10% weight gain | 3 | − 0.2373 | 0.2527 | 5.83 (p < 0.000) |
| 5–10% weight gain | 19 | − 0.0321 | 0.1294 | |
| < 5% weight gain | 120 | − 0.0549 | 0.2233 | |
| < 5% weight loss | 227 | − 0.0196 | 0.1960 | |
| 5–10% weight loss | 150 | 0.0124 | 0.1538 | |
| > 10% weight loss | 203 | 0.0448 | 0.1946 | |
| Changes in EQ-5D-3L from 12 to 24 months | ||||
|---|---|---|---|---|
| % weight change from 12 to 24 months | N | Mean | Standard deviation | F-statistic (p value) |
| All participants | 620 | − 0.0135 | 0.1874 | |
| > 10% weight gain | 44 | − 0.0026 | 0.2408 | 0.20 (0.962) |
| 5–10% weight gain | 116 | − 0.0191 | 0.1635 | |
| < 5% weight gain | 291 | − 0.0187 | 0.1909 | |
| < 5% weight loss | 129 | − 0.0019 | 0.1861 | |
| 5–10% weight loss | 26 | − 0.0062 | 0.1919 | |
| > 10% weight loss | 14 | − 0.0125 | 0.1241 | |
| Changes in EQ-5D-3L from 12 months to 5 years | ||||
|---|---|---|---|---|
| % weight change from 12 months to 5 years | N | Mean | Standard deviation | F-statistic (p value) |
| All participants | 465 | − 0.0494 | 0.2343 | |
| > 10% weight gain | 112 | − 0.1068 | 0.2453 | 3.86 (0.002) |
| 5–10% weight gain | 108 | − 0.0639 | 0.2394 | |
| < 5% weight gain | 123 | − 0.0332 | 0.2364 | |
| < 5% weight loss | 72 | − 0.0282 | 0.0180 | |
| 5–10% weight loss | 34 | − 0.0018 | 0.1548 | |
| > 10% weight loss | 16 | 0.1266 | 0.3387 | |
This table demonstrates the average change in EQ-5D-3L across periods of observation in the trial. The study sample has been segmented by percentage change in weight to illustrate how change in EQ-5D differs for those experiencing weight loss and weight gain. The F statistics are generated from One Way Analysis of Variance