Table 4.

Regression estimates predicting change in EQ-5D-3L conditional on changes in BMI, including stratification by weight loss or weight gain

	Model specification 4: linear relationship		Model specification 5: asymmetric relationship		Model specification 6: multi-morbidity score
	Coefficient estimate	Standard error	Coefficient estimate	Standard error	Coefficient Estimate	Standard error
Change in BMI	− 0.0111	0.0019***	− 0.0146	0.0041***	− 0.0173	0.0052***
Change in BMI during weight loss			0.0059	0.0057	0.0089	0.0072
Baseline EQ-5D	− 0.0878	0.0217***	− 0.0890	0.0218***	− 0.0840	0.0236***
12 week intervention	0.0052	0.0105	0.0049	0.0105	− 0.0059	0.0111
52 week intervention	− 0.0080	0.0086	− 0.0083	0.0086	− 0.010	0.0097
New comorbidity					− 0.0112	0.0138
Constant	0.0574	0.0196***	0.0633	0.0205***	0.0620	0.0222**
Observations	2616		2616		2093

This table reports the ordinary least squares regression output for three model specifications to estimate the association between change in BMI and change in EQ-5D-3L. The table reports analyses without imputation of missing values. Model specification 4 includes change BMI and baseline BMI as variables. Model specification 5 includes an interaction term for change in BMI during periods of weight loss. Model specification 6 include the effects of comorbidities. Statistical significance at three thresholds are indicated by asterisks *** < 0.001 ** < 0.01 * < 0.05