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. 2022 Apr 28;33(10):2049–2102. doi: 10.1007/s00198-021-05900-y

Table 5.

Increases in BMD and associated estimated fracture risk reduction (FNIH Study) (Larger improvements in DXA-based BMD are associated with greater reductions in fracture risk, particularly for vertebral and hip fractures [62

% increase in BMD % reduction in vertebral fracture % reduction in hip fracture
At total hip
2% 28% 16%
4% 51% 29%
6% 66% 40%
At femoral neck
2% 28% 15%
4% 55% 32%
6% 72% 46%
At lumbar spine
2% 28% 22%
4% 62% 38%
6% 79% 51%