. Author manuscript; available in PMC: 2024 Dec 1.

Published in final edited form as: Epilepsia. 2022 Apr 16;64(Suppl 4):S124–S133. doi: 10.1111/epi.17252

TABLE 2.

Seizure forecasting results with the three selected architectures

Subject	Architecture 1, 3/200					Architecture 2, 5/25					Architecture 3, BiLSTM
Subject	AUC	Se	TIW/FAR	p	IoC	AUC	Se	TIW/FAR	p	IoC	AUC	Se	TIW/FAR	p	IoC
E02	.83	70	20.7/5.0	.001^a	50.3 (21.3)	.72	70	41.2/9.9	.045^a	35.0 (35.0)	.74	70	39.1/9.4	.033^a	34.9 (34.7)
E04	.76	67	17.5/4.2	.008^a	51.3 (17.1)	.65	67	35.2/8.4	.095	n.s.	.59	67	48.1/11.5	.258	n.s.
E06	.71	75	24.7/6.0	.040^a	52.8 (18.7)	.64	75	58.3/14.0	.393	n.s.	.78	75	25.1/6.0	.041^a	54.3 (21.0)
E09	.71	73	29.9/7.1	.003^a	42.7 (18.2)	.59	73	44.4/10.7	.039^a	30.2 (21.2)	.64	73	42.2/10.1	.027^a	34.4 (20.1)
S01	.50	64	65.7/15.8	.614	n.s.	.81	73	10.9/2.6	<.001^a	60.7 (15.0)	.79	73	13.6/3.3	<.001^a	61.2 (13.9)
S02	.37	40	41.0/9.8	.633	n.s.	.75	60	27.2/6.5	.104	n.s.	.74	80	36.3/8.7	.048^a	50.9 (25.0)
Mean (SD)	.65 (.17)^b	71.3 (3.5)^c	23.2 (5.4)/5.6 (1.3)^c	–	–	.69 (.08)^b	72.0 (1.7)^c	32.2 (18.5)/7.7 (4.4)^c	–	–	.74 (.08)^b	74.2 (3.7)^c	31.3 (11.8)/7.5 (2.8)^c	–	–

Abbreviations: AUC, area under the receiver operating characteristic curve; FAR, mean false alarm rate in hours/day; IoC, improvement over chance: mean (SD) improvement in percentage sensitivity of the forecast compared to 100 randomly generated AUCs after shuffling seizure times, at the same time in warning; n.s., nonsignificant; Se, percentage sensitivity; TIW, time in warning as a percentage of recording in a high-risk state.

p< .05.

Mean (SD) across all subjects.

Mean (SD) of significant forecasts.