TABLE 2.

Baseline CSF and DAT imaging pathology

Outcome	PD	PD‐OD	PD‐RBD	PD‐DH	P Value	Post Hoc P Value
DAT imaging
Low putamen	0.69 (0.25)	0.61 (0.22)	0.68 (0.32)	0.64 (0.22)	0.024 a	I vs. II
Low caudate	1.88 (0.51)	1.66 (0.52)	1.84 (0.60)	1.75 (0.51)	0.007 a	I vs. II
Mean putamen	0.86 (0.28)	0.75 (0.22)	0.85 (0.37)	0.78 (0.27)	0.011 a	I vs. II
Mean caudate	2.06 (0.52)	1.85 (0.51)	2.02 (0.62)	1.91 (0.55)	0.021 b	I vs. II
CSF, markers, pg/mL
α‐syn	1465 (620)	1574 (720)	1444 (632)	1542 (725)	0.810 a	–
Aβ42	899 (369)	885 (405)	954 (481)	911 (427)	0.740 a	–
Tau	159 (51)	167 (66)	167 (61)	180 (69)	0.161 a	–
P‐tau	13.4 (5.0)	14.0 (6.5)	13.8 (6.1)	15.3 (6.7)	0.294 a	–

^a Kruskal–Wallis test.

^b P values are calculated using 1‐way analysis of variance.

Data was shown as mean (SD). Abbreviations: CSF, cerebrospinal fluid; DAT, dopamine transporter; PD, Parkinson's disease; OD, olfactory dysfunction; RBD, rapid eye movement sleep behavior disorder; DH, dual hit; α‐syn, α‐synuclein; Aβ42, β‐amyloid 1–42; P‐tau, phosphorylated tau at threonine 181.