. 2022 Oct 7;5(10):e2235331. doi: 10.1001/jamanetworkopen.2022.35331

Table 2. Multivariable Model of Receipt of 30 mL/kg of Intravenous Fluids Within 6 Hours of Septic Shock Onset (N = 2287).

Variable^a	aOR (95% CI)	P value
HFrEF	0.63 (0.47-0.85)	.002
Age^b	0.98 (0.98-0.99)	<.001
Race
Black	1 [Reference]	NA
White	0.87 (0.69-1.10)	.87
Other^c	0.95 (0.52-1.72)	.26
Sex
Female	1 [Reference]	NA
Male	0.71 (0.58-0.87)	.001
Elixhauser Comorbidity Index^d	0.91 (0.87-0.95)	<.001
SOFA score in 6 h^e	1.09 (1.01-1.18)	.03

Abbreviations: aOR, adjusted odds ratio; HFrEF, heart failure with reduced ejection fraction; SOFA, Sequential Organ Failure Assessment.

^{^a}

Hospital of admission included as a random effect.

^{^b}

The aOR corresponds to a 1-year increase in age.

^{^c}

American Indian or Alaska Native, Asian, Chinese, Filipino, Hawaiian or Other Pacific Islander, Middle Eastern, Native American, or Pacific Islander.

^{^d}

A method of categorizing the comorbid conditions of patients based on the International Classification of Diseases, Ninth Revision diagnosis codes found in administrative data (range, 0-31; with higher score indicating greater comorbidity burden). The aOR corresponds to a 1-point change in the Elixhauser Comorbidity Index.

^{^e}

Corresponds to the severity of organ dysfunction, reflecting 6 organ systems (cardiovascular, hepatic, hematologic, respiratory, neurologic, and kidney), each with a score range of 0 to 4 points, with a total score range of 0 to 24 points. The aOR corresponds to a 1-point increase in SOFA score.