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. 2022 Sep;11(9):1472–1488. doi: 10.21037/gs-22-449

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2022 Gland Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Expression profiles of the 10 hub genes in human cancer and normal tissues. Representative immunohistochemical images of (A) CCNA2 (https://www.proteinatlas.org/ENSG00000145386-CCNA2/tissue/breast) and (https://www.proteinatlas.org/ENSG00000145386-CCNA2/pathology/breast+cancer#img), (B) CDK1 (https://www.proteinatlas.org/ENSG00000170312-CDK1/tissue/breast) and (https://www.proteinatlas.org/ENSG00000170312-CDK1/pathology/breast+cancer#img), (C) CENPF (https://www.proteinatlas.org/ENSG00000117724-CENPF/tissue/breast) and (https://www.proteinatlas.org/ENSG00000117724-CENPF/pathology/breast+cancer#img), (D) KIF2C (https://www.proteinatlas.org/ENSG00000142945-KIF2C/tissue/breast) and (https://www.proteinatlas.org/ENSG00000142945-KIF2C/pathology/breast+cancer#img), (E) KIF4A (https://www.proteinatlas.org/ENSG00000090889-KIF4A/tissue/breast) and (https://www.proteinatlas.org/ENSG00000090889-KIF4A/pathology/breast+cancer#img), (F) MELK (https://www.proteinatlas.org/ENSG00000165304-MELK/tissue/breast) and (https://www.proteinatlas.org/ENSG00000165304-MELK/pathology/breast+cancer#img), (G) PBK (https://www.proteinatlas.org/ENSG00000168078-PBK/tissue/breast) and (https://www.proteinatlas.org/ENSG00000168078-PBK/pathology/breast+cancer#img), (H) PRC1 (https://www.proteinatlas.org/ENSG00000198901-PRC1/tissue/breast) and (https://www.proteinatlas.org/ENSG00000198901-PRC1/pathology/breast+cancer#img), (I) TOP2A (https://www.proteinatlas.org/ENSG00000131747-TOP2A/tissue/breast) and (https://www.proteinatlas.org/ENSG00000131747-TOP2A/pathology/breast+cancer#img), and (J) TPX2 (https://www.proteinatlas.org/ENSG00000088325-TPX2/tissue/breast) and (https://www.proteinatlas.org/ENSG00000088325-TPX2/pathology/breast+cancer#img) protein expression in normal breast and cancer tissues. (A-J) are from the HPA (images are available from v21.1 proteinatlas.org). Counterstained with hematoxylin, 100 µm.