Table 2. Proportions of the polymorphism at codon 129 and 219 in PRNP in different diseases from 2006 to 2021 (%).

Disease	Codon 129				Codon 219
	M129M	M129V	V129V		E219E	E219K	K219K
Abbreviation: PRNP=prion protein gene; sCJD=sporadic Creutzfeldt-Jacob disease; gPrD=genetic prion disease.
sCJD	98.5	1.5	0		98.9	1.1	0
gPrD	98.2	1.8	0		98.7	1.3	0
non-CJD	96.8	3.2	0		93.5	6.5	0
Referred	97.6	2.4	0		96.3	3.7	0