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. 2022 Aug 9;144(5):1053–1055. doi: 10.1007/s00401-022-02474-9

Table 1.

Comparison between patient’s demographics and tumor features of AKT1- and NF2-mutant spinal meningiomas

All tumors (n = 50) AKT1-mutant
(n = 15)
NF2-mutant
(n = 32)
P value
Median age (years) 66 71 65 0.032
Female sex 38 7/15 (46.6%) 30/32 (94%) 0.0006
Thoracic spine location 28 4/15 (26.6%) 24/32 (75%) 0.0034
Cervical spine location 21 11/15 (73.3%) 7/32 (21.8%) 0.0012
Ventral or ventro-lateral location to spinal cord 28 13/15 (87%) 14/32 (40.6%) 0.010
Dorsal or dorso-lateral location to spinal cord 22 2/15 (13.3%) 19/32 (59.3%) 0.0043
Meningothelial histology 24 14/15 (93.3%) 7/32 (21.8%) 0.0001
Tumor calcification 17 None 17/32 (53.2%) 0.0002

Bold indicates significance (P < 0.05)