Table 1.
Demographic and clinical characteristics of the study groups
| Healthy-Weight (n=49) | Obese (n=40) | P value | |
|---|---|---|---|
| Demographics | |||
| Age (years) | 8.79 ± 1.27 | 8.93 ± 1.37 | NS |
| Male (n (%)) | 27 (55.10) | 24 (60.00) | NS |
| Hispanic (n (%)) | 29 (59.18) | 27 (67.50) | NS |
| Pulmonary function indices * | |||
| FVC | 95.02 ± 13.01 | 103.23 ± 12.00 | <0.01 |
| FEV 1 | 91.41 ± 15.57 | 94.18 ± 16.55 | 0.42 |
| FEV 1 /FVC ratio | 84.24 ± 7.46 | 79.75 ± 8.33 | 0.01 |
| FEF25–75% | 79.27 ± 29.38 | 74.51 ± 29.05 | 0.48 |
| TLC | 93.36 ± 11.78 | 95.85 ± 13.99 | 0.38 |
| RV | 113.49 ± 31.49 | 100.43 ± 38.14 | 0.09 |
| RV/TLC ratio | 29.38 ± 5.90 | 24.80 ± 6.77 | <0.01 |
| ERV | 88.36 ± 26.54 | 71.13 ± 19.15 | <0.01 |
| FRC | 106.41 ± 22.91 | 90.38 ± 22.83 | <0.01 |
| IC | 81.36 ± 13.14 | 98.73 ± 14.91 | <0.01 |
| Measures of asthma severity and control | |||
| CASI | 7.95 ± 3.47 | 8.58 ± 3.20 | 0.38 |
| ACT | 19.58 ± 4.60 | 19.62 ± 4.53 | 0.97 |
All variables are reported as mean ± SD other than sex and ethnicity which are reported as proportions (n(%).
*
Pulmonary function indices are reported as percent-predicted values other than the ratios which are reported as percentages. A CASI score of greater than 3 is suggestive of higher asthma severity and an ACT score of 19 and higher is suggestive of good asthma control.