Table 3.
Statistical tests performance
1. | Sensitivity: Proportion of subjects who test positive for a specific condition among a group of people who have the condition; how well a test can detect a specific condition in people who actually have the condition |
2. | Specificity: Proportion of subjects who test negative for a specific condition among a group of people who do not have the condition |
3. | Receiver operator characteristic (ROC) curve: A plot of the true-positive rate versus the false-positive rate for all possible cut points of a biomarker |
4. | Incidence: number of individuals who develop a specific disease during a particular time period |
5. | *Positive predictive value (PPV): Likelihood that a person who has a positive test result does have the disease |
6. | *Negative predictive value (NPV): Likelihood that a person who has a negative test result indeed does not have the disease |
Require biomarker cut-point values and depend on incidence of disease