Table 5.
Negative and positive predictive values for the Elastic net LR model and outcome of in-hospital mortality.
| Performance goal | Patients above/below threshold | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|---|---|
| Training | Maximizing NPV | 409/65 | 1 (0.96,1.0) | 0.17 (0.13,0.21) | 0.2 (0.16,0.24) | 1 (0.94,1.0) |
| Maximizing PPV | 3/471 | 0.04 (0.01,0.1) | 1.0 (0.99,1) | 1.0 (0.29,1.0) | 0.83 (0.8,0.87) | |
| Internal validation | Maximizing NPV | 165/73 | 0.93 (0.8,0.98) | 0.36 (0.29,0.43) | 0.23 (0.17,0.3) | 0.96 (0.88,0.99) |
| Maximizing PPV | 1/237 | 0.02 (0,0.13) | 1.0 (0.98,1.0) | 1.0 (0.03,1.0) | 0.83 (0.78,0.88) | |
| External validation | Maximizing NPV | 308/37 | 0.98 (0.95,1) | 0.18 (0.13,0.25) | 0.51 (0.45,0.56) | 0.92 (0.78,0.98) |
| Maximizing PPV | 40/305 | 0.22 (0.16,0.29) | 0.97 (0.94,0.99) | 0.88 (0.73,0.96) | 0.59 (0.54,0.65) |