Table 1.

Histological parameters used to establish a scoring system based on the Updated Sydney System and De Witte et al. and Gastritis overall scoring system [13]

Parameter		Scoring
Inflammatory cells (lymphocytes, plasm cells, neutrophils, eosinophils)	Absent	0
	Mild infiltration (<5 cells per HPF)	1
	Moderate infiltration (≥5–20 cells per HPF)	2
	Severe infiltration (≥20 cells per HPF)	3
Lymphoid follicles in the superficial and deep mucosa	No aggregates of lymphoid cells	0
	Presence of one aggregate of lymphoid cells with minimal organization into a follicular structure	1
	Presence of at least one large follicle measuring at least 300 µm in diameter and/or more than one small aggregate of lymphoid cells per histological section	2
	At least two large lymphoid follicles measuring at least 300 µm in diameter per histological section and/or deformation of the mucosal caused by large lymphoid follicles	3
Gastritis overall scoring system
Score
0	Normal
1	Mild gastritis
2	Moderate gastritis
≥ 3	Severe gastritis

HPF: high power field, i.e., 400× total magnification.