Table 2.
Sleeping time in mice was induced by the neuropharmacological activity of the extracts by seeping time test
| Group | Dosage (mg/kg) | Latency period | Sleeping time | Effect (%) |
|---|---|---|---|---|
| Control | 10ml/kg | 10.0±0.71 | 35.8±1.98 | 0 |
| Standard | 0.5 | 3.2±0.37 | 181.2±14.52 | 506.15* |
| EE | 50 | 6.2±0.80 | 73.4±4.63 | 205.03 |
| EE | 100 | 4.4±0.51 | 138.6±5.41 | 387.15* |
| EE | 200 | 2.2±0.25 | 243.6±8.85 | 680.45* |
| AE | 50 | 6.4±0.81 | 64.2±3.08 | 179.33 |
| AE | 100 | 4.8±0.58 | 118.0±6.40 | 329.61* |
| AE | 200 | 2.6±0.43 | 215.6±8.01 | 602.23* |
| ETAE | 50 | 7.4±0.67 | 66.4±2.46 | 185.47 |
| ETAE | 100 | 4.6±0.40 | 124.4±7.44 | 347.49* |
| ETAE | 200 | 2.4±0.29 | 228.0±13.82 | 636.87* |
EE: ethanol extract; AE: acetone extract; ETAE: ethyl acetate extract. Results are presented as Mean±SEM (n=5), *P<0.05, statistically significant in comparison with the control group (one-way ANOVA followed by Dunnett’s test)