Table 3.
Neuropharmacological activity of the extracts by hole cross method
| Group | Dosage | Quantity of movement (percentage of movements inhibition) | ||||
|---|---|---|---|---|---|---|
| 0 min | 30 min | 60 min | 90 min | 120 min | ||
| Control | 10 ml/kg | 3.8±0.86 | 3.8±0.37 | 4.8±0.86 | 4.8±0.80 | 4.6±0.40 |
| Standard | 1 | 2.2±0.58* | 2.0±0.32* | 1.4±0.51* | 1.8±0.58* | 1.6±0.60* |
| EE | 100 | 3.0±0.45* | 3.6±0.60 | 3.8±1.46 | 3.4±1.91 | 3.4±0.68 |
| EE | 200 | 2.8±0.49* | 3.0±1.00 | 2.8±0.86* | 1.6±0.51* | 2.6±0.24* |
| AE | 100 | 2.6±1.08* | 3.8±0.58 | 4.4±1.16 | 4.2±1.83 | 3.0±0.71 |
| AE | 200 | 4.0±0.32 | 3.4±0.75 | 3.4±0.60 | 3.2±1.07* | 2.8±0.58* |
| ETAE | 100 | 3.6±0.81 | 3.2±0.58* | 3.8±1.46 | 2.8±1.71* | 3.0±0.71 |
| ETAE | 200 | 4.2±0.73 | 4.2±0.66 | 3.6±0.51 | 3.2±0.86* | 3.0±0.55 |
EE: ethanol extract; AE: acetone extract; ETAE: ethyl acetate extract. Results are presented as Mean±SEM (n=5), *P<0.05, statistically significant in comparison with the control group (one-way ANOVA followed by Dunnett’s test)