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Table 5.

Neuropharmacological activity of the extracts by open field test

Group Dosage Movement Quantity (percentage of movements inhibition)
0 min 30 min 60 min 90 min 120 min
Control 10 ml/kg 36.2±5.54 37.6±3.85 35.8±6.11 39.6±4.11 40.2±3.28
Standard 1 14.8±3.47* 15.2±4.02* 18.8±4.55* 20.2±4.14* 18.8±4.12*
EE 100 34.8±2.65 28.2±2.85 30.4±1.66 29.8±2.48* 27.0±2.76*
EE 200 24.6±3.44 26.8±2.92 26.8±2.11 23.4±1.66* 26.6±1.50*
AE 100 32.0±3.19 27.2±2.35 28.4±2.11 28.6±2.04* 35.2±4.61
AE 200 27.4±2.30 28.2±2.76 28.4±4.85 25.6±1.29* 28.6±3.19*
ETAE 100 35.2±3.77 30.4±3.17 24.2±3.31* 23.0±2.61* 28.4±1.83*
ETAE 200 16.6±2.20* 28.6±2.52 25.4±4.30* 26.8±1.46* 27.2±2.20*

EE: ethanol extract; AE: acetone extract; ETAE: ethyl acetate. Results are presented as Mean± SEM (n=5), *P<0.05, statistically significant in comparison with the control group (two-way ANOVA followed by Bonferroni's test)