Table 1. Characteristics of the CADASIL and control groups.
| Characteristics | Control (n=12) | CADASIL (n=6) | t/χ2 | P |
| CADASIL: cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; WMH: white matter hyperintensity. aFisher exact test. | ||||
| Demographic data | ||||
| Male, n (%) | 5 (41.67) | 4 (66.67) | 0.620a | |
| Female, n (%) | 7 (58.33) | 2 (33.33) | ||
| Age (years), mean±SD | 45.67±10.58 | 52.00±16.11 | 1.008 | 0.329 |
| Risk factors, n (%) | ||||
| Hypertension | 4 (33.33) | 3 (50.00) | 0.627a | |
| Diabetes | 1 (8.33) | 1 (16.67) | 1.000a | |
| Hyperlipidemia | 2 (16.67) | 1 (16.67) | 1.000a | |
| Smoking | 2 (16.67) | 0 (0.00) | 0.529a | |
| Other data, mean±SD | ||||
| Systolic pressure (mmHg) | 131.00±10.60 | 135.60±18.61 | 0.519 | 0.626 |
| Diastolic pressure (mmHg) | 80.33±5.19 | 89.80±19.83 | 1.053 | 0.349 |
| Triglycerides (mmol/L) | 1.31±0.70 | 1.08±0.28 | 0.711 | 0.491 |
| Total cholesterol (mmol/L) | 4.07±0.69 | 3.62±0.78 | 1.103 | 0.292 |
| HDL-C (mmol/L) | 1.18±0.25 | 1.22±0.11 | 0.404 | 0.694 |
| LDL-C (mmol/L) | 2.40±0.52 | 1.94±0.69 | 1.396 | 0.188 |
| Glucose (mmol/L) | 4.74±0.61 | 5.43±1.83 | 0.818 | 0.456 |
| WMH volume (mL) | 0.39±0.36 | 22.85±12.99 | 4.233 | 0.008 |