Table 1.
Inclusion, exclusion and PICO (Population Intervention Comparison and Outcome) criteria for this review
| Inclusion criteria | Exclusion criteria | |
|---|---|---|
|
-Published articles in English or with translation freely available (from any period) -Full text accessibility -Study designs (any of): Randomised control trials (RCTs), non-RCTs, prospective and retrospective cohort studies, cross-sectional studies, case–control studies, case series |
-Adipose tissue obtained from animals or cadavers -Enzyme use prior to device/system administration or enzymatic-based devices/systems -Devices/systems involved in lipotransfer or the harvesting process of adipose tissue eg. AquaVage, and LipiVage [78] -Case reports, review articles, abstracts, letters and non-peer reviewed articles -Studies reported in any other language apart from English with no translation |
|
| PICO criteria | ||
| Population | Human subjects (any age) including source of adipose tissue | |
| Intervention/Exposure | Use of commercially available devices and systems to mechanically process lipoaspirate to obtain fresh cells | |
| Control/Comparator | Any other lipoaspirate-processing technique | |
| Outcome(s) | Primary | Cell concentration at point of isolation, without further expansion in culture |
| Secondary | Cell viability, phenotypic analysis and clinical application of the cellular product | |