FIGURE 2.

Role of retina glial cells in IRDs. Schematic representation of the three glial cell types in the retina (Müller cells, microglia and astrocytes) and their main functions and changes in healthy and disease retina. The three cells work together in different processes affecting retinal homeostasis in healthy retina (A). During the course of retinal degeneration, these cells secrete pro-inflammatory factors and promote proliferation, migration and phagocytosis, increasing inflammatory signals in the tissue (B).