TABLE 2.
Simplified representative data to calculate the percent change of different parameters possibly affecting the glomerular sieving coefficient (GSC) of albumin.
| Magnitude | Percent change | |
|---|---|---|
| GSC dextran equivalent radius to albumin (Comper and Russo, 2009) | 0.03 | 4900 |
| Apparent GSC albumin healthy rats (Tojo and Endou, 1992) (micropuncture) | 0.0006 | |
| GSC albumin nephrotic rats (Comper and Russo, 2009) | 0.03 | 4900 |
| Apparent GSC albumin healthy rats (Tojo and Endou, 1992) | 0.0006 | |
| A2 os GAG physiological ionic strength/units (Comper and Laurent, 1978) | 1.3–3.3 | 27 |
| A2 os GAG high ionic strength/units (Comper and Laurent, 1978) | 1.3–2.2 | |
| A* normalized§ albumin interaction with uncharged polysaccharide, physiological ionic strength (Comper and Laurent, 1978) | 1.0 | 0 |
| A* normalized§ albumin interaction with GAG (Ogston and Preston, 1966; Ogston and Silpananta, 1970; Shaw and Schy, 1977) | 1.0 |
Normalization was performed by using the ratio of the interaction coefficient to the second virial coefficient of the polysaccharide.