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. 2022 Sep 26;13:991756. doi: 10.3389/fphys.2022.991756

TABLE 2.

Simplified representative data to calculate the percent change of different parameters possibly affecting the glomerular sieving coefficient (GSC) of albumin.

Magnitude Percent change
GSC dextran equivalent radius to albumin (Comper and Russo, 2009) 0.03 4900
Apparent GSC albumin healthy rats (Tojo and Endou, 1992) (micropuncture) 0.0006
GSC albumin nephrotic rats (Comper and Russo, 2009) 0.03 4900
Apparent GSC albumin healthy rats (Tojo and Endou, 1992) 0.0006
A2 os GAG physiological ionic strength/units (Comper and Laurent, 1978) 1.3–3.3 27
A2 os GAG high ionic strength/units (Comper and Laurent, 1978) 1.3–2.2
A* normalized§ albumin interaction with uncharged polysaccharide, physiological ionic strength (Comper and Laurent, 1978) 1.0 0
A* normalized§ albumin interaction with GAG (Ogston and Preston, 1966; Ogston and Silpananta, 1970; Shaw and Schy, 1977) 1.0

Normalization was performed by using the ratio of the interaction coefficient to the second virial coefficient of the polysaccharide.