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. 2022 Sep 26;13:999078. doi: 10.3389/fphar.2022.999078

TABLE 2.

Body weight, morbidity, and mortality after acute toxicity studies of withametelin and daturaolone at selected doses.

Withametelin (mg/kg) Daturaolone (mg/kg)
0 5 50 300 5 50 300
Body weight (g)
Day 1 210.8 ± 4.24 215.36 ± 4.32 214.21 ± 3.23 215.63 ± 3.96 218.29 ± 2.34 215.67 ± 5.61 217.89 ± 5.58
Day 7 232.4 ± 3.76 236.38 ± 5.48 239.21 ± 3.76 225 ± 4.32 239.23 ± 4.45 235.14 ± 3.39 237.85 ± 5.11
Day 14 256.4 ± 3.76 261.31 ± 5.48 252.40 ± 5.31 238 ± 5.17 264.46 ± 3.90 261.29 ± 4.22 258.39 ± 6.16
Morbidity
 Day 1 0/3 0/3 0/3 0/3 0/3 0/3 0/3
 Day 7 0/3 0/3 0/3 2/3 0/3 0/3 0/3
 Day 14 0/3 0/3 0/3 0/3 0/3 0/3 0/3
Mortality
 Day 1 0/3 0/3 0/3 0/3 0/3 0/3 0/3
 Day 7 0/3 0/3 0/3 0/3 0/3 0/3 0/3
 Day 14 0/3 0/3 0/3 0/3 0/3 0/3 0/3