TABLE 1.

Human articles summary.

Assay	Model	Relevant information	Year	Reference
Triglyceride level lowering	Human	Twelve-week trial using Bacillus licheniformis in combination with another spore forming bacilli probiotics have remarkable triglyceride lowering	2020	Campbell et al., 2020
Radiotherapy side effects protection	Human	In pediatric patients with central nervous system tumor, probiotics may have a critical preventive function in the etiology of gastrointestinal symptoms caused by radiotherapy. Gut barrier function, innate immunity, and intestinal repairmen can all be influenced by Bacillus licheniformis probiotics. Probiotics given prophylactically during irradiation therapy for CNS tumor patients can alleviate RT-related symptoms and improve cancer patients’ quality of life, in part by lowering inflammatory reactions and gastrointestinal toxicity.	2017	Du et al., 2018
Endotoxemia, Triglyceride lowering and inflammatory biomarkers	Human	After 30 days of B. licheniformis with other spore-based probiotic supplementation, dietary endotoxin, triglycerides, and possibly systemic inflammation were reduced. Changes in the gut microbiome, gut permeability, or a combination of the two could be the underlying cause of the observed reductions in post-prandial endotoxemia. More research is needed to confirm if a longer period of treatment with a spore-based probiotic leads to further health benefits.	2017	McFarlin et al., 2017

Related to human clinical trials of B. licheniformis, assay focuses, and main outcomes.