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. 2022 Sep 26;12:917353. doi: 10.3389/fonc.2022.917353

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Copyright © 2022 Nie, Lv, Chen, Xu, Wang, Liu, Wang, Zhao, He and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier curve of PFS (A) and OS (B) in the general population. Kaplan-Meier curve of PFS (C) and OS (D) in the regorafenib plus sintilimab(RS), and fruquintinib plus sintilimab(FS) group.