Table 4.

Treatment-related adverse events (TRAEs).

Adverse Event	All grade N, %	≥ Grade3 N, %
Hematologic
Decreased white blood count	6 (8.3)	0 (0)
Anemia	11 (15.3)	0 (0)
Decreased platelet	4 (5.6)	1 (1.4)
Increased ALT/AST	13 (18.1)	2 (2.8)
Hyperbilirubinemia	5 (6.9)	0 (0)
Non- Hematologic
Fatigue	23 (31.9)	0 (0)
Decreased appetite	22 (30.6)	0 (0)
Oral mucositis	14 (19.4)	0 (0)
Diarrhea	10 (13.9)	0 (0)
Secondary hypertension	17 (23.6)	4 (5.6)
Hand-foot syndrome	8 (11.1)	2 (2.8)
Proteinuria	4 (5.6)	0 (0)
Rash	4 (5.6)	1 (1.4)
Pneumonitis	3 (4.2)	1 (1.4)
Pyrexia	2 (2.8)	0 (0)
Hypothyroidism	15 (20.8)	0