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Antitumour immunity of NK cells was regulated by m6A modification. (A) YTHDF2 is essential for IL-15-mediated NK-cell survival and proliferation by the STAT5-YTHDF2 positive feedback loop. (B) Mettle3 ablation in NK cells changed the hemostasis, infiltration and function of NK cells by modifying SHP-2 mRNA in the tumor microenvironment.
