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. 2022 Sep 20;25(9):658–664. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2022.102.21

表 2.

基因多态性与肺癌发病风险相关性的Logistic回归分析

Logistic regression analysis of associations between gene polymorphisms and the risk of lung cancer

SNP Control group (n=445) Case group (n=270) OR (95%CI) P OR (95%CI)* P *
Data were calculated by Logistic regression with adjustment for age, gender, and pathological type. *adjusted by age/gender/pathological type; SNP: single nucleotide polymorphism; OR: risk factor; CI: confidence interval.
CDH1 (rs201141645)
    AA 323 (72.6%) 270 (100%) 1
    A/C 50 (11.2%) 0 (0%) 0.997
    CC 72 (16.2%) 0 (0%) 0.996
FANCB (rs754552650)
    AA 121 (27.2%) 253 (93.7%) 1 1
    A/G 234 (52.6%) 17 (6.3%) 0.034 (0.020-0.057) < 0.001 0.035 (0.020-0.062) < 0.001
    GG 90 (20.2%) 0 (0%) 0.996 0.996
APC (rs149353082)
    CC 445 (100%) 269 (99.6%) 1
    C/G 0 (0%) 1 (0.4%) 0.999