表 2.
基因多态性与肺癌发病风险相关性的Logistic回归分析
Logistic regression analysis of associations between gene polymorphisms and the risk of lung cancer
| SNP | Control group (n=445) | Case group (n=270) | OR (95%CI) | P | OR (95%CI)* | P * |
| Data were calculated by Logistic regression with adjustment for age, gender, and pathological type. *adjusted by age/gender/pathological type; SNP: single nucleotide polymorphism; OR: risk factor; CI: confidence interval. | ||||||
| CDH1 (rs201141645) | ||||||
| AA | 323 (72.6%) | 270 (100%) | 1 | |||
| A/C | 50 (11.2%) | 0 (0%) | 0.997 | |||
| CC | 72 (16.2%) | 0 (0%) | 0.996 | |||
| FANCB (rs754552650) | ||||||
| AA | 121 (27.2%) | 253 (93.7%) | 1 | 1 | ||
| A/G | 234 (52.6%) | 17 (6.3%) | 0.034 (0.020-0.057) | < 0.001 | 0.035 (0.020-0.062) | < 0.001 |
| GG | 90 (20.2%) | 0 (0%) | 0.996 | 0.996 | ||
| APC (rs149353082) | ||||||
| CC | 445 (100%) | 269 (99.6%) | 1 | |||
| C/G | 0 (0%) | 1 (0.4%) | 0.999 | |||