表 3.

FANCB基因rs754552650与肺癌风险相关性的分层分析

Stratified analyses of FANCB (rs754552650) for association with lung cancer risk

Variable	Control group (n=445)	Case group (n=270)	OR (95%CI)	P
In the pathological type stratified analysis, the pathological type of the case group was compared with the control group as a whole.
Age
≤60 yr
AA	93 (20.9%)	94 (34.8%)	1
A/G	176 (39.6%)	8 (3.0%)	0.045 (0.021-0.097)	< 0.001
GG	69 (15.5%)	0 (0%)
> 60 yr
AA	28 (6.3%)	159 (58.9%)	1
A/G	58 (13.0%)	9 (3.3%)	0.027 (0.012-0.061)	< 0.001
GG	21 (4.7%)	0 (0%)
Gender
Female
AA	62 (13.9%)	111 (41.1%)	1
A/G	130 (29.2%)	15 (5.6%)	0.064 (0.035-0.120)	< 0.001
GG	51 (11.4%)	0 (0%)
Male
AA	59 (13.3%)	142 (52.6%)	1
A/G	104 (23.4%)	2 (0.7%)	0.008 (0.002-0.033)	< 0.001
GG	39 (8.8%)	0 (0%)
Histological type
ADC
AA	121 (27.2%)	183 (67.8%)	1
A/G	324 (72.8%)	17 (6.3%)	0.249 (0.145-0.426)	< 0.001
SCC
AA	121 (27.2%)	46 (17.0%)
A/G	324 (72.8%)	0 (0%)
ASC
AA	121 (27.2%)	3 (1.1%)
A/G	324 (72.8%)	0 (0%)
SCLC
AA	121 (27.2%)	15 (5.6%)
A/G	324 (72.8%)	0 (0%)
Others
AA	121 (27.2%)	6 (2.2%)
A/G	324 (72.8%)	0 (0%)