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. 2022 Sep 26;13:999823. doi: 10.3389/fimmu.2022.999823

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Copyright © 2022 Wang, Liu, Li, Luo, Liu and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Status of ferredoxin 1 (FDX1) expression in malignancies. (A) Profile of FDX1 expression in distinct human tumors and homologous healthy tissues. (B) Differences in FDX1 expression between KIRC tissues and adjacent healthy tissues. (C) Differences in FDX1 expression between normal samples (obtained using GTEx data) and adjoining clear cell renal cell carcinoma (ccRCC) tissues and samples. (D) Differences in FDX1 expression between ccRCC samples and corresponding adjoining samples. (E) Receiver operating characteristic curve for FDX1 expression in normal samples (obtained using GTEx data) and adjoining ccRCC tissues and samples. (F) FDX1 protein expression was considerably downregulated in tumor tissues compared to non-paired normal tissues. (*p < 0.05, **p < 0.01, ***p < 0.001, and ns, no statistical difference).