Table 3.
Univariable and multivariable cox analyses of RFS.
| Subject characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (<70 years, >=70 years) | 1.190 (0.745-1.923) | 0.468 | ||
| Sex (female, male) | 1.132 (0.656-1.949) | 0.667 | ||
| Smoking (no, yes) | 1.560 (0.942-2.525) | 0.085 | 0.862 (0.515-1.449) | 0.566 |
| Drinking (no, yes) | 0.744 (0.445-1.259) | 0.275 | ||
| Hypertension (no, yes) | 1.226 (0.747-2.036) | 0.410 | ||
| Diabetes (no, yes) | 1.038 (0.529-2.028) | 0.923 | ||
| Grade (low, high) | 2.164 (1.280-3.690) | 0.004 | 2.040 (1.149-3.371) | 0.015 |
| CIS (no, yes) | 3.773 (2.105-7.142) | <0.001 | 2.040 (1.075-3.571) | 0.030 |
| T stage (Ta, T1) | 4.739 (2.463-8.849) | <0.001 | 3.030 (1.666-6.666) | 0.001 |
| Tumor number (single, multiple) | 2.816 (1.639-5.00) | <0.001 | 3.125 (1.754-5.555) | < 0.001 |
| Tumor diameter (<3cm, ≥3cm) | 3.030 (1.886-4.901) | <0.001 | 1.785 (1.334-3.030) | 0.036 |
| Sarcopenia (no, yes) | 3.225 (1.960-5.263) | <0.001 | 2.040 (1.250-3.333) | 0.005 |
| SII (low, high) | 2.631 (1.666-4.166) | <0.001 | 2.127 (1.298-3.571) | 0.003 |
RFS, relapse-free survival; CIS, Carcinoma in Situ; BMI, Body Mass Index; SII, Systemic Immune-Inflammation Index.