Table 1.
Subgroup | Receptor | Alleles | Mutation mechanism | Base changes | Phenotype |
---|---|---|---|---|---|
ALV-A/K | Tva | Tva | - | - | Sensitive |
Tvar | Base mutation | C/G 168 mRNA | Resistant | ||
Tvar2 | Exon 1 insert 4 bp | 284CTGC287 | Resistant | ||
Tvar3 | Intron 1 miss 10 bp | 507ACCCCGCCCC516 | Reduce susceptibility | ||
Tvar4 | Intron 1 miss 5 bp | 507ACCCC511 | Reduce susceptibility | ||
Tvar5 | Intron 1 miss 10 bp | 502CGCTCACCCC511 | Reduce susceptibility | ||
Tvar6 | Intron 1 miss 15 bp | 502CGCTCACCCCGCCCC516 | Reduce susceptibility | ||
ALV-B/D/E | Tvb | Tvbs1 | - | - | Sensitive to subgroups B/D/E |
Tvbs3 | Base mutation | T/A 184 mRNA | Sensitive to subgroups B/D | ||
Tvbr | Base mutation | C/T 172 mRNA | Resistant | ||
ALV-C | Tvc | Tvc | - | - | Sensitive |
Tvcr | Base mutation | C/A165 mRNA | Resistant | ||
ALV-J | NHE1 | NHE1 | - | - | Sensitive |
NHE1∆ | Base mutation | W38 | Resistant |
“-” means no change. The superscript numbers indicate gene loci