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. 2022 Oct 4;72(725):e891–e898. doi: 10.3399/BJGP.2021.0711

Table 2.

Characteristics of people with B12 deficiency including self-medication status/safety, type of diagnosis (B12 versus pernicious anaemia), general health status, and health literacy levels

Variable Diagnosis, n (%) χ2-test (P-value)a Paired t-testb (P-value)

Vitamin B12 deficiency Pernicious anaemia
Health status
Good/excellent 207 (16.0) 181 (14.0) 1.518 (0.218)
Fair/poor 451 (34.7) 458 (35.3)

Health literacy (self-assessed)
Always/often 24 (1.9) 20 (1.5) 1.761 (0.624)
Sometimes 63 (4.9) 71 (5.5)
Rarely 73 (5.6) 61 (4.7)
Never 498 (38.3) 487 (37.5)

Country of residence (region)
East Midlands 36 (3.5) 31 (3) 15.839 (0.147)
Ireland 12 (0.9) 9 (0.7)
London 15 (1.4) 22 (2.1)
North East 19 (1.8) 38 (3.7)
North West 96 (9.2) 101 (9.7)
Northern Ireland 17 (1.3) 7 (0.7)
Scotland 16 (1.5) 25 (2.4)
South East 87 (8.4) 78 (7.5)
South West 76 (7.3) 54 (5.2)
Wales 137 (10.6) 66 (6.3)
West Midlands 31 (3) 38 (3.7)
Yorkshire/Humberside 44 (4.2) 44 (4.2)

Self-medication
Yes 435 (33.5) 368 (28.3) 9.997 (0.002 )
No 222 (17.1) 270 (20.8)

Self-medication via injection
Yes 279 (21.5) 229 (17.7) 5.862 (0.016 )
No 379 (29.2) 410 (31.6)

PC PMOS total −17.42 (0.071)
a

Pearson’s χ2 test for all factors. Bold text denotes significance at the 0.05 level.

b

Paired t-test with 1298 degrees of freedom. PC PMOS = Primary Care Patient Measure of Safety.