Table 2.
IRRs of clinical events recorded 6 months, 1, 3, and 5 years before the index date (CPRD GOLD)
| Clinical events | 6 months, IRR (95% CI) | 1 year, IRR (95% CI) | 3 years, IRR (95% CI) | 5 years, IRR (95% CI) |
|---|---|---|---|---|
| Seborrheic dermatitis | 2.34 (1.82 to 3.00) | 1.97 (1.65 to 2.35) | 1.49 (1.33 to 1.66) | 1.27 (1.13 to 1.38) |
| Eczema | 2.23 (1.99 to 2.50) | 1.90 (1.76 to 2.05) | 1.41 (1.35 to 1.48) | 1.23 (1.18 to 1.28) |
| Tinea corporis | 2.52 (2.09 to 3.03) | 1.99 (1.74 to 2.27) | 1.43 (1.32 to 1.56) | 1.25 (1.17 to 1.34) |
| Candida skin infections | 1.46 (1.32 to 1.74) | 1.44 (1.29 to 1.61) | 1.28 (1.20 to 1.37) | 1.15 (1.08 to 1.21) |
| Pityriasis rosea | 7.82 (4.09 to 14.95) | 3.24 (2.24 to 5.27) | 1.71 (1.28 to 2.27) | 1.38 (1.09 to 1.75) |
| Dry skin | 2.05 (1.54 to 2.72) | 1.52 (1.24 to 1.86) | 1.38 (1.22 to 1.57) | 1.08 (1.06 to 1.30) |
| Rash | 4.00 (3.62 to 4.41) | 2.71 (2.53 to 2.92) | 1.63 (1.55 to 1.71) | 1.32 (1.27 to 1.38) |
| Skin texture changes | 2.17 (1.69 to 2.29) | 1.55 (1.39 to 1.77) | 1.23 (1.14 to 1.31) | 1.13 (1.06 to 1.20) |
| Itching | 1.39 (1.00 to 1.93) | 1.54 (1.22 to 1.94) | 1.26 (1.10 to 1.45) | 1.18 (1.05 to 1.32) |
| Topical corticosteroids | 2.58 (2.39 to 2.79) | 1.97 (1.88 to 2.07) | 1.46 (1.42 to 1.50) | 1.24 (1.21 to 1.27) |
| Topical antifungal treatment | 2.32 (2.08 to 2.59) | 1.92 (1.78 to 2.07) | 1.43 (1.36 to 1.49) | 1.24 (1.20 to 1.29) |
CPRD = Clinical Practice Research Datalink. IRR = incidence rate ratio.