Figure 5.

The expressions of ERK-associated inflammatory factors were inhibited in septic mice BMT TLR9-deficient myeloid cells. (a) The cardiac protein levels of phosphorylated levels of ERK1/2 and downstream TNF-α, IFN-γ, and IL-1β as well as the apoptotic associated proteins: cytochrome C and cleaved-caspase-3/-9 were tested by western blot in WT and TLR9^−/− BMT mice of control and sepsis groups. (b) The statistic data tested by western blot in each group. ^∗ <0.05 and ^∗∗ <0.01 vs. septic mice BMT WT myeloid cells.