Box plots showing the ANOVA results for reticular basement membrane (RBM) thickness (A) and RBM cells per mm of RBM (B) in healthy control (HC), patients with asthma COPD overlap (ACO), asthma, COPD exsmokers (COPD-ES), COPD current smokers (COPD-CS), and normal lung function smokers (NLFS). The box-and-whisker plots showing the minimum and the maximum value, the lower and the upper quartile and the horizontal line as median. P < 0.05 is significantly different. Insignificant P values are not shown in the plot. COPD, chronic obstructive pulmonary disease.