Figure 6.

Box plots showing the Mann–Whitney test results for epithelial thickness (A), epithelial cells/mm reticular basement membrane (RBM) (B), goblet cells/mm of RBM (C), RBM thickness (D), RBM cells/mm RBM (E), lamina propria cells/mm² (F), and smooth muscle area (G) in patients with asthma COPD overlap (ACO) and asthma with ICS and no-ICS. The box-and-whisker plots showing the minimum and the maximum value, the lower and the upper quartile and the horizontal line as median. P < 0.05 is significantly different between ICS and no-ICS groups. COPD, chronic obstructive pulmonary disease. ICS, inhaled corticosteroids.