Figure 4.

A and B: linear regression analysis demonstrating the relationships between age and ICA percent change in mean blood flow (A) and ICA percent change in shear rate (n = 58, females = 31; B). Solid line represents the regression fit for males, and dotted line represents the regression fit for female participants. Hierarchical regression models (P value and R²) are presented for the relationship with age (model 1), the relationship with sex (model 2), and the moderator relationship of the sex-dependent relationship with age (model 3). Slope coefficients (β) of the relationship with age are presented for males and females separately (model 3). ICA, internal carotid artery.