Table 3.
(a) Univariate analysis of potential risk factors for post-operative infections following radical gastrectomy for stage II/III gastric cancer (n = 2352). (b) Multivariate analysis of potential risk factors for post-operative infections following radical gastrectomy for stage II/III gastric cancer (n = 2352).
| (a) | ||||
|---|---|---|---|---|
| Variables | Infections (n = 160) | Non-infection (n = 2192) | χ2 value | P value |
| Sex (Male: Female) | 115/45 | 1448/744 | 2.263 | 0.132 |
| Age (years) ≥ 65/< 65 | 48/112 | 499/1693 | 4.374 | 0.036 |
| Body mass index (kg/m2) ≥ 25/< 25 | 35/125 | 303/1889 | 7.857 | 0.005 |
| ASA score ≥ 3/<3 | 27/133 | 214/1978 | 8.202 | 0.004 |
| Comorbidity; yes/no | 63/97 | 642/1550 | 7.228 | 0.007 |
| Pre-operative hemoglobin (g/L) ≥ 100/< 100 | 110/50 | 1673/519 | 4.663 | 0.031 |
| Neo-adjuvant chemotherapy; yes/no | 11/149 | 247/1945 | 2.947 | 0.086 |
| Extent of gastric resection; subtotal/total | 107/53 | 1583/609 | 2.104 | 0.147 |
| Operation time (min) ≥ 240/< 240* | 70/89 | 475/1716 | 41.554 | <0.001 |
| Intra-operative blood loss (mL) ≥ 300/< 300 | 50/110 | 455/1737 | 9.737 | 0.002 |
| TNM stage†; III/II | 119/41 | 1614/578 | 0.043 | 0.837 |
| PNI ≥ 43.9/< 43.9 | 101/59 | 1618/574 | 8.661 | 0.003 |
| (b) | |||
|---|---|---|---|
| Variables | Odds Ratio [OR] | 95% Confidence Interval [CI] | P value |
| Operation time ≥ 240 min | 2.861 | 2.050–3.992 | <0.001 |
| PNI < 43.9 | 1.694 | 1.200–2.392 | 0.003 |
| Comorbidity | 1.557 | 1.109–2.187 | 0.011 |
| Body mass index ≥ 25 kg/m2 | 1.607 | 1.064–2.425 | 0.024 |
ASA American Society of Anesthesiology, PNI Prognostic nutritional index.
*The operation time was missed for one patient in each group.
†Tumor stages are based on 8th edition of the Union for International Cancer Control TNM classification.