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. 2022 Oct 10;12:16977. doi: 10.1038/s41598-022-21013-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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SEM present a series of images of CaP deposition on the surface of the composite discs compared to CSMA. 60% CaP formulation displays the highest quantity of precipitants on the surface, followed by 50 and 40% formulations respectively. Raman microscopy on the first bottom row shows the highest peak at 50% formulation followed by 60 and 40. Subsequently, the presence of CaP precipitates observed via SEM microscopy was confirmed through XRD analysis 1, 10, and 28-days post SBF immersion and incubation.