Table 2.
BM-MSCs group (n = 10) | HA group (n = 10) | P-value | |
---|---|---|---|
Age (years)a,c | 56.7 ± 4.83 | 59.1 ± 4.04 | 0.244 |
Gender, female (male) | 4 (6) | 8 (2) | |
Height (cm)a,c | 163.8 ± 9.27 | 156.6 ± 10.01 | 0.116 |
Weight (kg)a,c | 67.6 ± 8.75 | 64.1 ± 9.93 | 0.415 |
BMI (kg/m2)a,d | 25.4 ± 3.84 | 26.0 ± 1.95 | > 0.999 |
Kellgren-Lawrence graded | > 0.999 | ||
1 | 0 | 0 | |
2 | 8 | 9 | |
3 | 2 | 1 | |
4 | 0 | 0 | |
WOMAC | |||
Total scorea,c | 40.7 ± 26.01 | 38.1 ± 20.20 | 0.806 |
Pain scorea,c | 8.2 ± 5.37 | 7.6 ± 3.03 | 0.763 |
Stiffness scorea,d | 3.8 ± 2.49 | 4.2 ± 1.93 | 0.682 |
Physical functiona,d | 28.7 ± 18.73 | 32.9 ± 15.17 | 0.517 |
Percentage scorea,c | 42.4 ± 27.09 | 39.7 ± 21.04 | 0.806 |
SF36 | |||
PFa,c | 49.0 ± 27.37 | 51.5 ± 21.48 | 0.823 |
RPa,d | 11.3 ± 13.44 | 5.0 ± 6.46 | 0.385 |
BPa,c | 47.3 ± 23.93 | 49.5 ± 16.95 | 0.594 |
GHa,d | 50.5 ± 12.57 | 52.0 ± 7.15 | 0.691 |
VTa,c | 30.0 ± 16.61 | 26.3 ± 18.11 | 0.635 |
SFa,c | 70.0 ± 24.44 | 73.8 ± 20.79 | 0.716 |
REa,d | 20.8 ± 12.58 | 11.7 ± 11.92 | 0.148 |
MHa,c | 35.0 ± 13.21 | 29.2 ± 9.42 | 0.272 |
PCSa,c | 39.5 ± 15.01 | 39.5 ± 9.03 | > 0.999 |
MCSa,c | 39.0 ± 11.38 | 35.2 ± 8.01 | 0.406 |
VAS | |||
At restb,d | 2.5 (1.00, 3.75) | 1.5 (0.75, 3.25) | 0.591 |
With a burdenb,d | 6.0 (3.75, 8.25) | 5.0 (3.50, 6.00) | 0.096 |
During physical activityb,d | 6.5 (4.63, 9.00) | 5.5 (4.00, 7.25) | 0.466 |
KSSa,d | 63.2 ± 18.40 | 63.2 ± 17.85 | 0.587 |
KSFSa,d | 73.5 ± 14.15 | 79.0 ± 8.76 | 0.235 |
Data presented in mean ± standard deviation.
Ordinal data presented as median (lower quartile, upper quartile).
Data analyzed by tow-sample t test with Welch's correction.
Data analyzed by Mann-Whitney U test. BMI: Body Mass Index; WOMAC: Western Ontario and McMaster Universities Arthritis Index; PF: physical functioning; RP: role-physical; BP: bodily pain; GH: general health; VT: vitality; SF: social functioning; RE: role-emotional; MH: mental health; PCS: physical component summary; MCS: mental component summary; VAS: visual analogue scale; KSS: knee society score; KSFS: knee society function score; BM-MSCs, bone marrow-derived mesenchymal stem cells; HA, hyaluronic acid.