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. 2022 Sep 27;10:1032318. doi: 10.3389/fbioe.2022.1032318

TABLE 2.

Clinical trials of photodynamic therapy on cancers.

Disease Clinical trial phase PSs Application of nanoparticles Outcomes NCT/Ref.
Skin cancer Phase II Radachlorin N.A. No side effects. Good tolerability Kochneva et al. (2010)
Barrett’s esophagus Phase II Photofrin N.A. Good effect. No obvious side effects Panjehpour et al. (2000)
Glioma Phase II Haemetaporphyrin derivative (HpD) N.A. Good effect. No obvious side effects Stylli et al. (2005)
Brain tumor Phase I Photofrin N.A. Treatment’s safety not confirmed NCT01682746
Bladder cancer Phase II Hexvix N.A. Toxicities exist NCT01303991