TABLE 8.

Comparison of plasma PDGF‐BB levels of different genotypes between control group and CHD group

SNPs	Genotype	Control group		CHD group		t	p
		n	PDGF‐BB (pg/ml)	n	PDGF‐BB (pg/ml)
rs1800817	AA	81	220.02 ± 105.72	215	259.89 ± 132.60	−2.430	0.016*
	AC + CC	7	271.27 ± 171.76	32	248.13 ± 132.73	0.397	0.694
	T		−1.166		0.468
	p		0.247		0.640
rs2285094	TT	54	231.92 ± 129.79	148	255.37 ± 123.55	−1.178	0.240
	TC	29	215.09 ± 79.30	91	261.37 ± 148.94	−1.600	0.112
	CC	5	191.81 ± 45.43	8	279.56 ± 97.42	−1.868	0.089
	F		0.429		0.163
	p		0.653		0.850

Note: PDGF‐BB level was shown by mean ± SD, and that between control group and CHD group of different genotypes was analyzed by t test (*p < 0.05). In control group or CHD group, the comparison between genotype AA group and genotype AC + CC group was analyzed by t test, and that among genotype TT, TC, CC groups was analyzed by univariate ANOVA (*p < 0.05).

Abbreviations: CHD, coronary heart disease; PDGF‐BB, platelet‐derived growth factor‐BB; SNP, single nucleotide polymorphism.