Table 3.

Factors associated with cognitive recovery in patients with post-stroke SCC.

	Univariate model		Full model a		Extended model b
	OR (95% CI)	P-value	OR (95% CI)	P-value	OR (95% CI)	P-value
Reported time of SCC
151–180 d	Reference group	0.019	Reference group	0.026	Reference group	0.039
121–150 d	0.82 (0.317–2.123)	0.683	0.596 (0.207–1.719)	0.338	0.551 (0.171–1.776)	0.318
91–120 d	0.318 (0.106–0.954)	0.041	0.279 (0.088–0.888)	0.031	0.203 (0.058–0.709)	0.012
61–90 d	0.526 (0.214–1.291)	0.161	0.386 (0.146–1.022)	0.055	0.34 (0.116–0.993)	0.048
31–60 d	0.487 (0.211–1.122)	0.091	0.389 (0.156–0.967)	0.042	0.417 (0.157–1.113)	0.081
15–30 d	0.304 (0.108–0.851)	0.023	0.218 (0.071–0.670)	0.008	0.222 (0.064–0.766)	0.017
within 14 d	0.286 (0.137–0.598)	0.001	0.254 (0.114–0.566)	0.001	0.247 (0.103–0.592)	0.002
For trend	0.825 (0.740–0.920)	0.001	0.818 (0.726–0.922)	0.001	0.825 (0.723–0.941)	0.004
Male sex	2.497 (1.500–4.154)	<0.001	2.451 (1.418–4.237)	0.001	4.84 (2.394–9.784)	<0.001
Level of education
Low (years of education <12)	Reference group		Reference group		Reference group
High (years of education ≥12)	2.235 (1.381–3.681)	0.001	1.278 (0.741–2.206)	0.378	1.158 (0.623–2.152)	0.644
Location
Cerebral cortex	0.317 (0.097–1.040)	0.058			0.256 (0.067–0.982)	0.047
Thalamus	2.335 (1.091–4.999)	0.029	2.658 (1.125–6.281)	0.026	2.97 (1.171–7.531)	0.022
Brain stem	0.243 (0.058–1.020)	0.053			0.189 (0.034–1.066)	0.059
MoCA score at baseline	1.478 (1.276–1.712)	<0.001	1.473 (1.258–1.725)	<0.001	1.543 (1.297–1.837)	<0.001
Tea intake	1.145 (0.705–1.861)	0.584			1.123 (0.607–2.075)	0.712
Coffee intake	3.056 (1.127–8.289)	0.028	4.071 (1.271–13.032)	0.018	8.667 (2.378–31.595)	0.001

^aFull Model: adjusted for level of education, sex, coffee intake, lesions location (Cerebral cortex, thalamus, brain stem).

^bExtended Model: adjusted for the variables in (Full model) plus all other comorbidities listed in Table 2.

SCC, Subjective cognitive complaints; MoCA, Montreal Cognitive Assessment; CI, confidence interval; OR, odds ratio.