TABLE 4.
Association between eGFR and TG with risk of incident NAFLD.
| eGFR, mL/min⋅1.73 m2 | Crude model | Model Ia | Model IIa |
|
|
|
|
|
| HR (95% CI) P-value | HR (95% CI) P-value | HR (95% CI) P-value | |
| eGFR | 0.979 (0.977, 0.981) <0.0001 | 0.985 (0.982, 0.987) <0.0001 | 0.984 (0.982, 0.987) <0.0001 |
| eGFR Quartile | |||
| <82.88 | Ref. | Ref. | Ref. |
| ≥82.88, <99.70 | 0.709 (0.638, 0.788) <0.0001 | 0.788 (0.706, 0.879) <0.0001 | 0.775 (0.694, 0.866) <0.0001 |
| ≥99.70, <116.56 | 0.444 (0.394, 0.500) <0.0001 | 0.599 (0.528, 0.679) <0.0001 | 0.603 (0.530, 0.687) <0.0001 |
| ≥116.56 | 0.238 (0.207, 0.275) <0.0001 | 0.369 (0.315, 0.431) <0.0001 | 0.382 (0.325, 0.449) <0.0001 |
| P for trend | <0.0001 | <0.0001 | <0.0001 |
|
| |||
| TG, mmol/L | Crude modelb | Model Ib | Model IIb |
|
| |||
| TG | 2.552 (2.435, 2.676) <0.0001 | 1.838 (1.743, 1.937) <0.0001 | 1.582 (1.490, 1.681) <0.0001 |
| TG group | |||
| <1.7 | Ref. | Ref. | Ref. |
| ≥1.7 | 3.952 (3.624, 4.309) <0.0001 | 2.235 (2.044, 2.445) <0.0001 | 1.732 (1.574, 1.905) <0.0001 |
| TG group | |||
| ≥1.7 | Ref. | Ref. | Ref. |
| <1.7 | 0.253 (0.232, 0.276) <0.0001 | 0.447 (0.409, 0.489) <0.0001 | 0.578 (0.525, 0.635) <0.0001 |
The crude model was adjusted for none.
Adjust Ia model was adjusted for: age, sex, BMI, SBP, DBP.
Adjust IIa model was adjusted for: age, sex, TG, ALT, ALB, GLB, BUN, GLU, HDL-c, LDL-c, BMI, SBP, DBP.
Adjust Ib model was adjusted for: age, sex, BMI, SBP, DBP.
Adjust IIb model was adjusted for: age, sex, eGFR, ALT, ALB, GLB, BUN, GLU, HDL-c, LDL-c, BMI, SBP, DBP.
CI, confidence interval; Ref, reference; HR, hazard ratio.