Table 3.
Multivariate Cox proportional hazard models for overall survival (OS), disease-free survival (DFS), and progression-free survival (PFS) in HCC patients.
| Variables | OS | DFS | PFS | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
| T stage | ||||||
| T1 | Reference | Reference | Reference | |||
| T2 | 0.61 (0.08–4.63) | 0.633 | 0.31 (0.04–2.46) | 0.266 | 0.48 (0.06–3.77) | 0.488 |
| T3 and T4 | 1.11 (0.15–8.18) | 0.922 | 0.97 (0.13–7.26) | 0.975 | 0.75 (0.10–5.83) | 0.786 |
| M stage | ||||||
| M0 | Reference | Reference | Reference | |||
| M1 | 1.91(0.44–8.37) | 0.391 | 4.38 (0.95–20.12) | 0.058 | 2.06 (0.60–7.09) | 0.254 |
| Tumor status | ||||||
| Tumor free | Reference | Reference | ||||
| With tumor | 1.70 (1.05–2.75) | 0.032 | 14.70 (8.57–25.21) | <0.001 | ||
| Pathologic stage | ||||||
| Stage I | Reference | Reference | Reference | |||
| Stage II and Stage III and Stage IV | 2.62 (0.35–19.95) | 0.351 | 4.63 (0.60–35.87) | 0.142 | 1.71(0.23–12.81) | 0.601 |
| Vascular invasion | ||||||
| No | Reference | |||||
| Yes | 1.66 (1.00–2.76) | 0.048 | ||||
| CEP192 | ||||||
| Low | Reference | Reference | Reference | |||
| High | 1.73 (1.07–2.81) | 0.025 | 3.25 (1.71–6.17) | <0.001 | 1.70 (0.71–1.61) | 0.752 |
The values in bold were statistically significant.