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. 2022 Sep 27;9:868812. doi: 10.3389/fmed.2022.868812

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Copyright © 2022 Olaisen, Richard, Beisvåg, Granlund, Røyset, Rué, Martinsen, Sandvik, Sokol and Fossmark.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially abundant fungal taxa between Crohn's disease (CD) patients currently using anti-TNF agents (Anti-TNF) (n = 11) compared to CD patients with no medical treatment (NT) (n = 18). (A) Relative abundance of fungal phyla in CD patients with no medical treatment (NT) and anti-TNF treated CD patients. (B) Fungal taxa overrepresented in anti-TNF-treated CD patients (green) and in CD patients with no medical treatment (NT) (red) illustrated in a histogram with Linear Discriminant Analysis (LDA) score computed using linear discriminant analysis effect size (LEfSe).