Table 1.
Demographic and clinical characteristics of Crohn's disease (CD) patients and healthy controls (HC).
| CD | HC | p -valuea | |
|---|---|---|---|
| Number of patients, n | 44 | 40 | |
| Male gender, n (%) | 24 (54.5%) | 19 (47.5%) | 0.52 |
| Age, years, mean (SD) | 42.2 (14.4) | 36.6 (12.9) | 0.07 |
| BMI, mean (SD) | 25.8 (4.8) | 26.6 (4.7) | 0.40 |
| Acid reflux medication, n (%) | 0.72 | ||
| PPI | 5 (11.4%) | 2 (5%) | |
| H2 blockers | 0 | 0 | |
| PPI on demand | 0 | 0 | |
| H2 blockers on demand | 1 (2.3%) | 1 (2.5%) | |
| Smoking, n (%) | 0.57 | ||
| Never smoker | 23 (52.3%) | 25 (62.5%) | |
| Active smoker | 5 (11.4%) | 5 (12.5%) | |
| Snuff | 10 (22.7%) | 8 (20%) | |
| Ex-smoker | 6 (13.6%) %) | 2 (5%) | |
| Laboratory values | |||
| Hb (g/dL), mean (SD) | 14.1 (1.5) | 14.5 (1.7) | 0.197 |
| Leukocytes (x109/L), median (IQR) | 6.4 (2.3) | 6.5 (2.3) | 0.50 |
| CRP (mg/L), median (IQR) | <5 (4) | <5 (0) | 0.017 |
a
Comparing CD (n = 44) with HC (n = 40) using Mann–Whitney U-test for skewed distributed continuous variables, independent t-test for normal distributed continuous variables, and Chi-square/Fisher exact test for categorical variables.